Wednesday, August 10, 2011

Takotsubo cardiomyopathy

The amuse-bouche today was a case of Takotsubo cardiomyopathy. A few points:
•It is also known as :Stress-induced cardiomyopathy, apical ballooning syndrome, or broken heart syndrome
•Characterize d by transient systolic dysfunction of the apical and/or mid segments of the left ventricle
–mimics myocardial infarction with ST segment changes
–absence of obstructive coronary artery disease
•Typically presets w. RSCP, but occassionaly with new onset dyspnea
–Women >> Men
–Often at time of intense physical or emiotional stress
•Pathogenesis not well understood
–? Catecholamine surge
–? Vasospasm

See a nice brief article in CMAJ here.

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