Tuesday, July 17, 2012

Shortness of breath - July 17, 2012


Thank you to team 5 for bringing the case and to Dr. Andrea Page for hosting.

Today, we discussed a case of an elderly man from a long-term care facility who presented with shortness of breath.  The differential diagnosis was quite wide, and we had the opportunity to discuss a few of them.

From an infectious perspective, this man is at risk of Health Care Associated Pneumonia (HCAP).  The significance being that he may be at risk for infections by organisms that may not be usually thought of the Community Acquired Pneumonia setting.  The Infectious Diseases Society of America (IDSA) Guideline (2005) about this topic can be found here and it lists the following as risk factors for HCAP:
- Hospitalization for 2 days or more in previous 90 days
- Residence in a nursing home or extended care facility
- Home infusion therapy (including antibitoics)
- Chronic dialysis within 30 days
- Home wound care
- Family member with multi-drug resistant pathogen

Dr. Page reminded us that much of the literature is based in the U.S. environment and that local ecology of organisms (rate of drug resistant organisms) may be quite different.  It is important to consider the local experience here.  If you are interested in this concept, here are 2 recent review papers:  Am J Med (2011) and Curr Opin Infect Dis (2012).

Also, it is important NOT to forget viral causes of pneumonia.  A recent Lancet paper on this topic can be found here.  You can find flu activities in Ontario and Toronto in the Flu Bulletin here (For 2 weeks ending July 7, 2012, Toronto showed sporadic activity).  For the 2 weeks ending on July 7, 2012, parainfluenza virus and entero/rhinovirus had the most number of positive specimens.

We also discussed briefly that patients born in the pre-war period (in Canada and Europe) are at risk of TB.

Other non-infectious causes including cardiac (heart failure, ischemia, pericarditis), volume overload from renal disease, pulmonary embolism, primary respiratory illness (COPD, interstitial lung disease) are also important considerations.

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