The Syndrome of "Leser and Trelat" came up today in our discussion. It is certainly not that common, but one we should know about. This is a rapid eruption of seborrheic keratoses which can be pruritic and have an inflammatory base. It is a paraneoplastic condition commonly associated with intraabdominal malignancies - particularly gastrointestinal adenocarcinoma.
Here is a case from NEJM.
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